Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetChymotrypsin-C(Homo sapiens (Human))
Sixera Pharma

US Patent
LigandPNGBDBM113297(US9695194, 14)
Affinity DataKi: <100nM ΔG°: <-41.6kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Chymotrypsin, bovine, 25 ug (Roche, sequence grade), Substrate S-2586 (Chromogenics, cat. no. 82 08 94). Chymotrypsin activity was determi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKallikrein-7(Homo sapiens (Human))
Sixera Pharma

US Patent
LigandPNGBDBM113297(US9695194, 14)
Affinity DataKi:  183nM ΔG°:  -40.0kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Recombinant human KLK7, Substrate S-2586 (Chromogenics, cat. no. 820894) KLK7 activity was determined at 37° C. in 10 mM Na phosphate ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin G(Homo sapiens (Human))
Sixera Pharma

US Patent
LigandPNGBDBM113297(US9695194, 14)
Affinity DataKi:  200nM ΔG°:  -39.8kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKallikrein-5 [D153N](Homo sapiens (Human))
Sixera Pharma

US Patent
LigandPNGBDBM113297(US9695194, 14)
Affinity DataKi:  600nM ΔG°:  -36.9kJ/molepH: 8.0 T: 2°CAssay Description:Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKallikrein-14(Homo sapiens (Human))
Sixera Pharma

US Patent
LigandPNGBDBM113297(US9695194, 14)
Affinity DataKi:  1.50E+3nM ΔG°:  -34.6kJ/molepH: 8.0 T: 2°CAssay Description:Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine protease 1(Homo sapiens (Human))
Sixera Pharma

US Patent
LigandPNGBDBM113297(US9695194, 14)
Affinity DataKi:  1.80E+3nM ΔG°:  -34.1kJ/molepH: 7.2 T: 2°CAssay Description:Materials: Trypsin, 100 ug (Roche, sequence grade, Mw 23500), Substrate S-2288 (Chromogenics, cat. no. 820852). Trypsin activity was determined at 3...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Homo sapiens (Human))
Sixera Pharma

US Patent
LigandPNGBDBM113297(US9695194, 14)
Affinity DataKi:  3.00E+3nM ΔG°:  -32.8kJ/molepH: 8.3 T: 2°CAssay Description:Materials: Thrombin (Chromogenics, cat. no. 820712), Substrate S-2288 (Chromogenics, cat. no. 82 08 52). Thrombin activity was determined at 37° ...More data for this Ligand-Target Pair
In DepthDetails US Patent