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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50343906(1-(2-(4-(2-(Methylsulfonyl)phenoxy)phenoxy)ethyl)p...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of purified COX2 assessed as formation of oxidized TMPD during reduction og PGG2 to PGH2 preincubated for 15 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50343906(1-(2-(4-(2-(Methylsulfonyl)phenoxy)phenoxy)ethyl)p...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50343906(1-(2-(4-(2-(Methylsulfonyl)phenoxy)phenoxy)ethyl)p...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human LTA4 hydrolase activity assessed as LTB4 production after 15 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50343906(1-(2-(4-(2-(Methylsulfonyl)phenoxy)phenoxy)ethyl)p...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-induced PGE2 production after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50343906(1-(2-(4-(2-(Methylsulfonyl)phenoxy)phenoxy)ethyl)p...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of purified COX1 assessed as formation of oxidized TMPD during reduction og PGG2 to PGH2 preincubated for 15 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed