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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
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Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Merck Research Laboratory
Curated by
ChEMBL
Ligand
BDBM50071873
(4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfinyl-phenyl...)
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Affinity Data
IC50: 5nM
Assay Description:
Inhibition of Mitogen-activated protein kinase p38 alpha
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Mitogen-activated protein kinase 14
(Rattus norvegicus)
Merck Research Laboratory
Curated by
ChEMBL
Ligand
BDBM50071873
(4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfinyl-phenyl...)
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Affinity Data
IC50: 5.10nM
Assay Description:
Inhibitory potency evaluated against rat p38 kinase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Glucagon receptor
(Homo sapiens (Human))
TBA
Ligand
BDBM50071873
(4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfinyl-phenyl...)
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Affinity Data
IC50: 5.30nM
Assay Description:
Antagonist activity at human glucagon receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
Patents
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In Depth
Details
Article
Copy BDB DOI
Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Merck Research Laboratory
Curated by
ChEMBL
Ligand
BDBM50071873
(4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfinyl-phenyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.30nM
Assay Description:
Inhibitory activity against p38-alpha kinase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 11
(Homo sapiens (Human))
Merck Research Laboratory
Curated by
ChEMBL
Ligand
BDBM50071873
(4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfinyl-phenyl...)
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Affinity Data
IC50: 8.10nM
Assay Description:
Inhibition of Mitogen-activated protein kinase p38 beta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human))
Merck Research Laboratory
Curated by
ChEMBL
Ligand
BDBM50071873
(4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfinyl-phenyl...)
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Affinity Data
IC50: 65nM
Assay Description:
Inhibition of c-Jun N-terminal kinase 2-beta 1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human))
Merck Research Laboratory
Curated by
ChEMBL
Ligand
BDBM50071873
(4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfinyl-phenyl...)
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Affinity Data
IC50: 470nM
Assay Description:
Inhibitino of RAF kinase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 9
(Homo sapiens (Human))
Merck Research Laboratory
Curated by
ChEMBL
Ligand
BDBM50071873
(4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfinyl-phenyl...)
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Affinity Data
IC50: 1.50E+3nM
Assay Description:
Inhibition of c-Jun N-terminal kinase 2-beta 1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 9
(Homo sapiens (Human))
Merck Research Laboratory
Curated by
ChEMBL
Ligand
BDBM50071873
(4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfinyl-phenyl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.61E+3nM
Assay Description:
Inhibition of c-Jun N-terminal kinase 2-alpha 2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Merck Research Laboratory
Curated by
ChEMBL
Ligand
BDBM50071873
(4-[2-(4-Fluoro-phenyl)-5-(4-methanesulfinyl-phenyl...)
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Affinity Data
IC50: 1.60E+4nM
Assay Description:
Inhibition of c-Jun N-terminal kinase 1-alpha 1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI