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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075756(4-(3-(4-fluorophenyl)-5-(4-(methylsulfinyl)phenyl)...)
Affinity DataIC50:  670nMAssay Description:Inhibitory activity against p38-alpha kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075756(4-(3-(4-fluorophenyl)-5-(4-(methylsulfinyl)phenyl)...)
Affinity DataIC50:  670nMAssay Description:Inhibition of p38alpha MAP kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50075756(4-(3-(4-fluorophenyl)-5-(4-(methylsulfinyl)phenyl)...)
Affinity DataIC50:  671nMAssay Description:Antagonist activity at human glucagon receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlucagon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50075756(4-(3-(4-fluorophenyl)-5-(4-(methylsulfinyl)phenyl)...)
Affinity DataIC50:  1.10E+3nMAssay Description:Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed