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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
18
hits in this display
Target
Melanocortin receptor 3
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
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Affinity Data
Ki: 690nM
Assay Description:
Binding affinity against human Melanocortin 3 receptor by gamma-MCH displacement.
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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In Depth
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Article
PubMed
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Target
Melanocortin receptor 4
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 730nM
Assay Description:
Binding affinity against Melanocortin 4 receptor by gamma-MCH displacement.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Melanocortin receptor 5
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.10E+3nM
Assay Description:
Binding affinity against human Melanocortin 5 receptor by gamma-MCH displacement.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.20nM
Assay Description:
Inhibition of [125I]NDP-MSH binding to Melanocortin 1 receptor expressed in HEK293 cells; (N = 4)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 3
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
Inhibition of [125I]NDP-MSH binding to Melanocortin 3 receptor expressed in HEK293 cells; (N = 4)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 45nM
Assay Description:
Inhibition of [125I]NDP-MSH binding to Melanocortin 4 receptor expressed in HEK293 cells; (N = 4)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 45nM
Assay Description:
Inhibition of [125I]NDP-MSH binding to Melanocortin 4 receptor expressed in HEK293 cells; (N = 4)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 5
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 330nM
Assay Description:
Inhibition of [125I]NDP-MSH binding to Melanocortin 5 receptor expressed in HEK293 cells; N = 4
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 5
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 330nM
Assay Description:
Inhibition of [125I]NDP-MSH binding to Melanocortin 5 receptor expressed in HEK293 cells; N = 4
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 3
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.70nM
Assay Description:
Intracellular cAMP accumulation in human Melanocortin 3 receptor functional assay.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 73nM
Assay Description:
Agonist activity at wild type human melanocortin-4 receptor expressed in HEK293 cells co-transfected with CRE/beta-galactosidase reporter gene assess...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 180nM
Assay Description:
Intracellular cAMP accumulation in Melanocortin 4 receptor functional assay.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 5
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 550nM
Assay Description:
Intracellular cAMP accumulation in human Melanocortin 5 receptor functional assay.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 70nM
Assay Description:
Inhibition of [125I]NDP-MSH binding to Melanocortin 1 receptor expressed in HEK293 cells; (N = 4)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 5
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 390nM
Assay Description:
Effective concentration for intracellular cAMP accumulation in human melanocortin 5 receptor expressing HEK 293 cells; (N = 4)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 70nM
Assay Description:
Effective concentration for intracellular cAMP accumulation in human melanocortin 1 receptor expressing HEK 293 cells; (N = 4)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 3
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 520nM
Assay Description:
Effective concentration for intracellular cAMP accumulation in human melanocortin 3 receptor expressing HEK 293 cells; (N = 4)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50134948
(CHEMBL437050 | H-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-A...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 65nM
Assay Description:
Effective concentration for intracellular cAMP accumulation in human melanocortin 4 receptor expressing HEK 293 cells; (N = 4)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI