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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
NAD-dependent protein deacetylase sirtuin-1
(Homo sapiens (Human))
Jiangsu University
Curated by
ChEMBL
Ligand
BDBM50152067
(CHEMBL3781397)
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Affinity Data
IC50: 2.30nM
Assay Description:
Inhibition of recombinant GST-tagged human SIRT1 using 0.3 mM H2N-HK-[N(epsilon)-acetyl-lysine]-LM-COOH as substrate measured after 10 mins HPLC anal...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
NAD-dependent protein deacetylase sirtuin-3, mitochondrial
(Homo sapiens (Human))
Jiangsu University
Curated by
ChEMBL
Ligand
BDBM50152067
(CHEMBL3781397)
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Copy InChI
Affinity Data
IC50: 43nM
Assay Description:
Inhibition of recombinant His6 tagged human SIRT3 using 0.105 mM H2N-HK-[N(epsilon)-acetyl-lysine]-LM-COOH as substrate measured after 10 mins HPLC a...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
NAD-dependent protein deacetylase sirtuin-2
(Homo sapiens (Human))
Jiangsu University
Curated by
ChEMBL
Ligand
BDBM50152067
(CHEMBL3781397)
Copy SMILES
Copy InChI
Affinity Data
IC50: 144nM
Assay Description:
Inhibition of recombinant His6 tagged human SIRT2 using 0.39 mM H2N-HK-[N(epsilon)-acetyl-lysine]-LM-COOH as substrate measured after 12 mins HPLC an...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI