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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257286(CHEMBL521807 | Lys-Lys(epsilon-thioAc)-Leu-Met)
Affinity DataIC50:  330nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) preincubated for 5 mins before addition of substrate measured after 1 hr by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Kuopio

Curated by ChEMBL
LigandPNGBDBM50257286(CHEMBL521807 | Lys-Lys(epsilon-thioAc)-Leu-Met)
Affinity DataIC50:  4.98E+4nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) preincubated for 5 mins before addition of substrate measured after 3 hrs by fluorescence-based assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed