Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
University Of ZüRich

Curated by ChEMBL

LigandBDBM50155997(((S)-1-{1-[(S)-4-((S)-1-Benzylcarbamoyl-2-methyl-p...)Copy SMILESCopy InChI

Affinity DataKi:  1.05E+4nMAssay Description:Binding affinity towards Beta-secretase determined using continuum electrostatics solvationMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 1(Homo sapiens (Human))
University Of ZüRich

Curated by ChEMBL

LigandBDBM16782(Substrate-based BACE-1 inhibitor, 24 | tert-butyl ...)Copy SMILESCopy InChI

Affinity DataKi:  1.05E+4nM ΔG°:  -29.6kJ/molepH: 4.5 T: 2°CAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI