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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 16 hits in this display   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Vernalis Research

Curated by PDSP Ki Database
LigandPNGBDBM50060418(5-Methylsulfanyl-6-trifluoromethyl-2,3-dihydro-ind...)
Affinity DataKi:  2.19nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Vernalis Research

Curated by PDSP Ki Database
LigandPNGBDBM50060418(5-Methylsulfanyl-6-trifluoromethyl-2,3-dihydro-ind...)
Affinity DataKi:  2.45nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Vernalis Research

Curated by PDSP Ki Database
LigandPNGBDBM50060418(5-Methylsulfanyl-6-trifluoromethyl-2,3-dihydro-ind...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 2C receptor expressed in HEK 293 cells using [3H]mesulergine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Vernalis Research

Curated by PDSP Ki Database
LigandPNGBDBM50060418(5-Methylsulfanyl-6-trifluoromethyl-2,3-dihydro-ind...)
Affinity DataKi:  13nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 2B receptor expressed in HEK 293 cells using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50060418(5-Methylsulfanyl-6-trifluoromethyl-2,3-dihydro-ind...)
Affinity DataKi:  398nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 2A receptor expressed in HEK 293 cells using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50060418(5-Methylsulfanyl-6-trifluoromethyl-2,3-dihydro-ind...)
Affinity DataKi:  550nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50060418(5-Methylsulfanyl-6-trifluoromethyl-2,3-dihydro-ind...)
Affinity DataIC50:  13nMAssay Description:Inhibition of heterologously expressed human cytochrome P450 1A2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50060418(5-Methylsulfanyl-6-trifluoromethyl-2,3-dihydro-ind...)
Affinity DataIC50:  13nMAssay Description:Inhibition of heterologously expressed human Cytochrome P450 1A2 at 500 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50060418(5-Methylsulfanyl-6-trifluoromethyl-2,3-dihydro-ind...)
Affinity DataIC50:  110nMAssay Description:Inhibition of heterologously expressed human Cytochrome P450 2D6 at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50060418(5-Methylsulfanyl-6-trifluoromethyl-2,3-dihydro-ind...)
Affinity DataIC50:  110nMAssay Description:Inhibition of heterologously expressed human cytochrome P450 2D6Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50060418(5-Methylsulfanyl-6-trifluoromethyl-2,3-dihydro-ind...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of heterologously expressed human cytochrome P450 2C9Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50060418(5-Methylsulfanyl-6-trifluoromethyl-2,3-dihydro-ind...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of heterologously expressed human Cytochrome P450 19A1 at 100 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50060418(5-Methylsulfanyl-6-trifluoromethyl-2,3-dihydro-ind...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of heterologously expressed human cytochrome P450 2C19Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50060418(5-Methylsulfanyl-6-trifluoromethyl-2,3-dihydro-ind...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of heterologously expressed human Cytochrome P450 2C9 at 100 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50060418(5-Methylsulfanyl-6-trifluoromethyl-2,3-dihydro-ind...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of heterologously expressed human Cytochrome P450 3A at 100 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50060418(5-Methylsulfanyl-6-trifluoromethyl-2,3-dihydro-ind...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of heterologously expressed human cytochrome P450 3A4Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed