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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Kinesin-like protein KIF11
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50293756
(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)
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Affinity Data
IC50: 520nM
Assay Description:
Inhibition of human kinesin spindle protein by endpoint assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50293756
(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)
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Affinity Data
IC50: >7.00E+3nM
Assay Description:
Inhibition of CYP2C9 preincubated with compound
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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CHEMBL
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PubMed
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50293756
(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)
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Copy InChI
Affinity Data
IC50: 1.40E+4nM
Assay Description:
Inhibition of CYP2C9 coincubated with compound
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50293756
(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.50E+4nM
Assay Description:
Inhibition of CYP2D6 preincubated with compound
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50293756
(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)
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Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of CYP3A4 coincubated with compound
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50293756
(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of CYP2D6 coincubated with compound
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kinesin-like protein KIF3B
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50293756
(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of Kif3B
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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antibodypedia
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PubMed
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Target
Kinesin heavy chain isoform 5A
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50293756
(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of nKHC
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
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CHEMBL
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Target
Kinesin-like protein KIF11
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50293756
(2-(4-(methylthio)phenylamino)-1-(2-(trifluoromethy...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.00E+3nM
Assay Description:
Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI