Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50315590(1-(2-(furan-2-yl)-5-(methylthio)-[1,2,4]triazolo[1...)
Affinity DataKi:  742nMAssay Description:Displacement of [3H]CGS21680 from adenosine A2A receptor in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50315590(1-(2-(furan-2-yl)-5-(methylthio)-[1,2,4]triazolo[1...)
Affinity DataKi:  2.20E+3nMAssay Description:Displacement of [125I]-I-AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50315590(1-(2-(furan-2-yl)-5-(methylthio)-[1,2,4]triazolo[1...)
Affinity DataKi:  3.44E+3nMAssay Description:Displacement of [3H]R-PIA from adenosine A1 receptor in rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50315590(1-(2-(furan-2-yl)-5-(methylthio)-[1,2,4]triazolo[1...)
Affinity DataEC50:  1.68E+4nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed