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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Prothrombin
(Homo sapiens (Human))
Pcmd
Curated by
PubChem BioAssay
Ligand
BDBM32832
((4-methylphenyl)-(5-methylsulfanyl-3-phenyl-1,2,4-...)
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Affinity Data
IC50: 28.0nM
pH: 7.5 T: 2°C
Assay Description:
HTS was performed using 217,350 compounds of the MLSCN library individually plated into 10ul 1536 compound plates at a concentration of 2.5 mM each, ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
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Target
Kallikrein-5
(Homo sapiens (Human))
Pcmd
Curated by
PubChem BioAssay
Ligand
BDBM32832
((4-methylphenyl)-(5-methylsulfanyl-3-phenyl-1,2,4-...)
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Affinity Data
IC50: 833nM
Assay Description:
Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
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Target
Coagulation factor XI
(Homo sapiens (Human))
Pcmd
Curated by
PubChem BioAssay
Ligand
BDBM32832
((4-methylphenyl)-(5-methylsulfanyl-3-phenyl-1,2,4-...)
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Affinity Data
IC50: 3.05E+3nM
pH: 7.4 T: 2°C
Assay Description:
Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI