Home
About
Info
Download
WebServices
Contact
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Kappa-type opioid receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50185807
(5-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 330nM
Assay Description:
Displacement of [3H]U-69593 from kappa opioid receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nociceptin receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50185807
(5-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 710nM
Assay Description:
Agonist activity at ORL1 receptor expressed in HEK293 cells by calciun flux assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50185807
(5-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.36E+3nM
Assay Description:
Displacement of [3H]DAMGO from mu opioid receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM50185807
(5-chloro-3-(1-(cyclooctylmethyl)piperidin-4-yl)-2-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.18E+3nM
Assay Description:
Displacement of [3H]DDPDE from delta opioid receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI