Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50348295(CHEMBL1800120)Copy SMILESCopy InChI

Affinity DataIC50:  8.20nMAssay Description:Inhibition of human 11beta-HSD-1 expressed in HEK293 cells assessed as [3H]cortisol level by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50348295(CHEMBL1800120)Copy SMILESCopy InChI

Affinity DataIC50:  4.31E+3nMAssay Description:Inhibition of mouse 11beta-HSD-1More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50348295(CHEMBL1800120)Copy SMILESCopy InChI

Affinity DataEC50:  150nMAssay Description:Transactivation of PXRMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI