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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human))
Merck Usa
Curated by
ChEMBL
Ligand
BDBM50206959
(CHEMBL3924257)
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Affinity Data
IC50: 7.90nM
Assay Description:
Inhibition of human CYP11B2-CLE9 expressed in Chinese hamster V79 cells using 11-deoxycorticosterone as substrate preincubated for 1 hr followed by s...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
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Article
PubMed
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Target
Aromatase
(Homo sapiens (Human))
Merck Usa
Curated by
ChEMBL
Ligand
BDBM50206959
(CHEMBL3924257)
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Affinity Data
IC50: 420nM
Assay Description:
Inhibition of CYP19 (unknown origin) using MFC as substrate and NADPH as cofactor preincubated for 10 mins with cofactor followed by substrate/enzyme...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human))
Merck Usa
Curated by
ChEMBL
Ligand
BDBM50206959
(CHEMBL3924257)
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Affinity Data
IC50: 930nM
Assay Description:
Inhibition of human CYP11B1-8C7 expressed in Chinese hamster V79 cells using 11-deoxycortisol as substrate preincubated for 1 hr followed by substrat...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Steroid 17-alpha-hydroxylase/17,20 lyase
(Homo sapiens (Human))
Merck Usa
Curated by
ChEMBL
Ligand
BDBM50206959
(CHEMBL3924257)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human CYP17 expressed in African green monkey COS7 cells using 17-hydroxypregnenolone as substrate preincubated for 1 hr followed by su...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Steroid 21-hydroxylase
(Homo sapiens (Human))
Merck Usa
Curated by
ChEMBL
Ligand
BDBM50206959
(CHEMBL3924257)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human CYP21 expressed in African green monkey COS7 cells using 17-hydroxypregnenolone as substrate preincubated for 1 hr followed by su...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Merck Usa
Curated by
ChEMBL
Ligand
BDBM50206959
(CHEMBL3924257)
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Affinity Data
IC50: 1.10E+4nM
Assay Description:
Inhibition of hepatic CYP3A4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI