Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Glucocorticoid receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50144457
(CHEMBL419633 | N-(3-Dibenzylamino-2-methyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 28nM
Assay Description:
Binding affinity against human Glucocorticoid receptor (GR) using [3H]-dexamethasone as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucocorticoid receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50144457
(CHEMBL419633 | N-(3-Dibenzylamino-2-methyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 28nM
Assay Description:
Inhibition of [3H]dexamethasone binding to human glucocorticoid receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucocorticoid receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50144457
(CHEMBL419633 | N-(3-Dibenzylamino-2-methyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 28nM
Assay Description:
Inhibition of [3H]-dexamethasone binding to glucocorticoid receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Androgen receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50144457
(CHEMBL419633 | N-(3-Dibenzylamino-2-methyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 170nM
Assay Description:
Displacement of [3H]-dexamethasone from human androgen receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucocorticoid receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50144457
(CHEMBL419633 | N-(3-Dibenzylamino-2-methyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 250nM
Assay Description:
Functional activity towards human Glucocorticoid receptor in genetically engineered cell line containing glucocorticoid response element and reporter...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucocorticoid receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50144457
(CHEMBL419633 | N-(3-Dibenzylamino-2-methyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 250nM
Assay Description:
Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucocorticoid receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50144457
(CHEMBL419633 | N-(3-Dibenzylamino-2-methyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 250nM
Assay Description:
Inhibition of glucocorticoid receptor dexamethasone response
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mineralocorticoid receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50144457
(CHEMBL419633 | N-(3-Dibenzylamino-2-methyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 310nM
Assay Description:
Displacement of [3H]-dexamethasone from human mineralocorticoid receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Progesterone receptor
(Homo sapiens (Human))
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM50144457
(CHEMBL419633 | N-(3-Dibenzylamino-2-methyl-phenyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.60E+3nM
Assay Description:
Displacement of [3H]-dexamethasone from human progesterone receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI