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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus)
Takeda Chemical Industries
Curated by
ChEMBL
Ligand
BDBM50006803
(2,3,5-Trimethyl-6-pyridin-3-ylmethyl-[1,4]benzoqui...)
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Affinity Data
IC50: 62nM
Assay Description:
The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Thromboxane-A synthase
(Homo sapiens (Human))
Takeda Chemical Industries
Curated by
ChEMBL
Ligand
BDBM50006803
(2,3,5-Trimethyl-6-pyridin-3-ylmethyl-[1,4]benzoqui...)
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Copy InChI
Affinity Data
IC50: 400nM
Assay Description:
Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus)
Takeda Chemical Industries
Curated by
ChEMBL
Ligand
BDBM50006803
(2,3,5-Trimethyl-6-pyridin-3-ylmethyl-[1,4]benzoqui...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 680nM
Assay Description:
Reduction of lipid peroxide formed in rat brain homogenates.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI