Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 6 hits in this display
BDBM161571(US9108983, Example 386 | US9108983, Example 449)
Ki: 0.130nMAssay Description:Binding affinity to recombinant wild-type Bcl-2 (unknown origin) using peptide probe incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
BDBM161571(US9108983, Example 386 | US9108983, Example 449)
Ki: 0.280nMAssay Description:Binding affinity to recombinant Bcl-2 D103E mutant (unknown origin) using peptide probe incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
BDBM161571(US9108983, Example 386 | US9108983, Example 449)
Ki: 0.280nMAssay Description:Binding affinity to recombinant Bcl-2 D103V mutant (unknown origin) using peptide probe incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
BDBM161571(US9108983, Example 386 | US9108983, Example 449)
Ki: 0.530nMAssay Description:Binding affinity to recombinant Bcl-2 D103Y mutant (unknown origin) using peptide probe incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
BDBM161571(US9108983, Example 386 | US9108983, Example 449)
BDBM161571(US9108983, Example 386 | US9108983, Example 449)
IC50: 2.60nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair