Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetLIM domain kinase 1(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL

LigandBDBM50130035(CHEMBL3629280)Copy SMILESCopy InChI

Affinity DataIC50:  85nMAssay Description:Inhibition of LIMK1 (unknown origin) using 1 uM cofilin as substrateMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL

LigandBDBM50130035(CHEMBL3629280)Copy SMILESCopy InChI

Affinity DataIC50:  4.51E+3nMAssay Description:Inhibition of ROCK2 (unknown origin) after 4 hrs using 1 uM STK2 as substrateMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI