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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
1
hit in this display
Target
ATP-sensitive inward rectifier potassium channel 1
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM161044
(US9108947, 19)
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Affinity Data
IC50: 245nM
pH: 7.4 T: 2°C
Assay Description:
Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...
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Reactome pathway
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Ligand Info
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US Patent
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