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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
ATP-sensitive inward rectifier potassium channel 1
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50116795
(CHEMBL3612807)
Copy SMILES
Copy InChI
Affinity Data
IC50: 18nM
Assay Description:
Inhibition of ROMK (unknown origin) expressed in HEK293 cells by electrophysiology assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-sensitive inward rectifier potassium channel 1
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50116795
(CHEMBL3612807)
Copy SMILES
Copy InChI
Affinity Data
IC50: 140nM
Assay Description:
Inhibition of ROMK (unknown origin) expressed in HEK293 cells by thallium flux assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-sensitive inward rectifier potassium channel 1
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50116795
(CHEMBL3612807)
Copy SMILES
Copy InChI
Affinity Data
IC50: 140nM
Assay Description:
Inhibition of human ROMK expressed in HEK293 cells after 30 mins by thallium flux assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50116795
(CHEMBL3612807)
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Copy InChI
Affinity Data
IC50: 1.20E+4nM
Assay Description:
Inhibition of human ERG expressed in HEK293 cells by electrophysiology assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50116795
(CHEMBL3612807)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.80E+4nM
Assay Description:
Displacement of [35S]MK499 from human ERG expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50116795
(CHEMBL3612807)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.80E+4nM
Assay Description:
Displacement of [35S]-MK499 from human ERG expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI