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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
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Target
Prostaglandin G/H synthase 2
(Ovis aries (Sheep))
Y.B. Chavan College Of Pharmacy
Ligand
BDBM38550
(3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...)
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Affinity Data
IC50: 3.50E+4nM
T: 2°C
Assay Description:
The COX-1/COX-2 inhibition assay was done using an enzyme immunoassay (EIA) kit. The reaction buffer (960 uL), containing 0.1 M Tris-HCl (pH 8.0), 5...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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ChEBI
PC cid
PC sid
Patents
Similars
In Depth
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Article
PubMed
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Target
Rho-associated protein kinase 2
(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM38550
(3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...)
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Affinity Data
IC50: >5.96E+4nM
Assay Description:
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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ChEBI
PC cid
PC sid
Patents
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In Depth
Details
PCBioAssay
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Target
Prostaglandin G/H synthase 1
(Ovis aries (Sheep))
Y.B. Chavan College Of Pharmacy
Ligand
BDBM38550
(3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...)
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Affinity Data
IC50: >1.00E+5nM
T: 2°C
Assay Description:
The COX-1/COX-2 inhibition assay was done using an enzyme immunoassay (EIA) kit. The reaction buffer (960 uL), containing 0.1 M Tris-HCl (pH 8.0), 5...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mevalonate kinase
(Streptococcus pneumoniae D39)
Srmlsc
Curated by
PubChem BioAssay
Ligand
BDBM38550
(3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...)
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Affinity Data
IC50: >1.00E+7nM
Assay Description:
Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
PC cid
PC sid
Patents
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Mevalonate kinase
(Streptococcus pneumoniae D39)
Srmlsc
Curated by
PubChem BioAssay
Ligand
BDBM38550
(3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+7nM
Assay Description:
Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
PC cid
PC sid
Patents
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Mevalonate kinase
(Streptococcus pneumoniae D39)
Srmlsc
Curated by
PubChem BioAssay
Ligand
BDBM38550
(3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+7nM
Assay Description:
Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
PC cid
PC sid
Patents
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Protein RecA
(Mycobacterium tuberculosis H37Rv)
Broad Institute
Curated by
PubChem BioAssay
Ligand
BDBM38550
(3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...)
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Affinity Data
EC50: 3.10E+3nM
Assay Description:
Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
PC cid
PC sid
Patents
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Protein RecA
(Mycobacterium tuberculosis H37Rv)
Broad Institute
Curated by
PubChem BioAssay
Ligand
BDBM38550
(3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.95E+3nM
Assay Description:
Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
PC cid
PC sid
Patents
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI