Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Y.B. Chavan College Of Pharmacy

LigandPNGBDBM38550(3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...)
Affinity DataIC50:  3.50E+4nMT: 2°CAssay Description:The COX-1/COX-2 inhibition assay was done using an enzyme immunoassay (EIA) kit. The reaction buffer (960 uL), containing 0.1 M Tris-HCl (pH 8.0), 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM38550(3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...)
Affinity DataIC50: >5.96E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Y.B. Chavan College Of Pharmacy

LigandPNGBDBM38550(3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...)
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:The COX-1/COX-2 inhibition assay was done using an enzyme immunoassay (EIA) kit. The reaction buffer (960 uL), containing 0.1 M Tris-HCl (pH 8.0), 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMevalonate kinase(Streptococcus pneumoniae D39)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM38550(3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...)
Affinity DataIC50: >1.00E+7nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMevalonate kinase(Streptococcus pneumoniae D39)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM38550(3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...)
Affinity DataIC50: >1.00E+7nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMevalonate kinase(Streptococcus pneumoniae D39)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM38550(3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...)
Affinity DataIC50: >1.00E+7nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis H37Rv)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM38550(3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...)
Affinity DataEC50:  3.10E+3nMAssay Description:Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis H37Rv)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM38550(3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...)
Affinity DataEC50:  2.95E+3nMAssay Description:Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay