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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Plasma kallikrein
(Homo sapiens (Human))
Kalvista Pharmceuticals
US Patent
Ligand
BDBM186869
(US9670157, 35 2,5-Dimethyl-1-(2-p-tolyl-thiazol-4-...)
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Affinity Data
IC50: 2.10E+3nM
Assay Description:
Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Plasma kallikrein
(Homo sapiens (Human))
Kalvista Pharmceuticals
US Patent
Ligand
BDBM186869
(US9670157, 35 2,5-Dimethyl-1-(2-p-tolyl-thiazol-4-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.10E+3nM
Assay Description:
Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Kallikrein-1
(Homo sapiens (Human))
Kalvista Pharmceuticals
US Patent
Ligand
BDBM186869
(US9670157, 35 2,5-Dimethyl-1-(2-p-tolyl-thiazol-4-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+4nM
Assay Description:
KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Kallikrein-1
(Homo sapiens (Human))
Kalvista Pharmceuticals
US Patent
Ligand
BDBM186869
(US9670157, 35 2,5-Dimethyl-1-(2-p-tolyl-thiazol-4-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
KLK1 inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI