Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istanbul University

Curated by ChEMBL

LigandBDBM50258299(1-({[5-(Aminosulfonyl)-3-(2,3,4,5,6-pentafluorophe...)Copy SMILESCopy InChI

Affinity DataKi:  0.880nMAssay Description:Inhibition of human recombinant CA2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Istanbul University

Curated by ChEMBL

LigandBDBM50258299(1-({[5-(Aminosulfonyl)-3-(2,3,4,5,6-pentafluorophe...)Copy SMILESCopy InChI

Affinity DataKi:  0.930nMAssay Description:Inhibition of human recombinant CA1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCarbonic anhydrase(Mycobacterium tuberculosis)
Istanbul University

Curated by ChEMBL

LigandBDBM50258299(1-({[5-(Aminosulfonyl)-3-(2,3,4,5,6-pentafluorophe...)Copy SMILESCopy InChI

Affinity DataKi:  0.930nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv3273 by by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCarbonic anhydrase(Candida albicans (Yeast))
Istanbul University

Curated by ChEMBL

LigandBDBM50258299(1-({[5-(Aminosulfonyl)-3-(2,3,4,5,6-pentafluorophe...)Copy SMILESCopy InChI

Affinity DataKi:  5.10nMAssay Description:inhibition of Candida albicans recombinant Nce103 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Istanbul University

Curated by ChEMBL

LigandBDBM50258299(1-({[5-(Aminosulfonyl)-3-(2,3,4,5,6-pentafluorophe...)Copy SMILESCopy InChI

Affinity DataKi:  9.70nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv1284 by by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI