Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL

LigandBDBM50083814(3-({1-[3-(1,4,5,6-Tetrahydro-pyrimidin-2-ylamino)-...)Copy SMILESCopy InChI

Affinity DataIC50:  28nMAssay Description:Inhibition of adhesion of integrin beta3-transfected HEK293 cells to fibrinogenMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL

LigandBDBM50083814(3-({1-[3-(1,4,5,6-Tetrahydro-pyrimidin-2-ylamino)-...)Copy SMILESCopy InChI

Affinity DataIC50:  66nMAssay Description:Inhibition of aggregation of human gel-purified platelets (GPIIbIIIa GPP)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI