Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50347568(CHEMBL1801735)Copy SMILESCopy InChI

Affinity DataIC50:  8.20nMAssay Description:Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50347568(CHEMBL1801735)Copy SMILESCopy InChI

Affinity DataEC50:  762nMAssay Description:Partial agonist activity at human PPARgamma-LBD/Gal4 DNA binding domain by transactivation assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI