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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Substance-P receptor
(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50030140
(CHEMBL281804 | [(S)-1-(3,5-Dimethyl-benzyloxycarbo...)
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Affinity Data
IC50: 125nM
Assay Description:
Binding affinity towards cloned neurokinin 1 receptor, based on the displacement of [125I]-labeled substance P
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Substance-P receptor
(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50030140
(CHEMBL281804 | [(S)-1-(3,5-Dimethyl-benzyloxycarbo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 125nM
Assay Description:
Tested against cloned human NK1 receptor by displacement of 125 I -labeled substance P expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Substance-K receptor
(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50030140
(CHEMBL281804 | [(S)-1-(3,5-Dimethyl-benzyloxycarbo...)
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Copy InChI
Affinity Data
IC50: >5.00E+3nM
Assay Description:
Binding affinity to the NK2 receptor assayed by displacement of [125I]-Neurokinin A
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuromedin-K receptor
(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50030140
(CHEMBL281804 | [(S)-1-(3,5-Dimethyl-benzyloxycarbo...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+3nM
Assay Description:
Affinity to NK3 receptors assayed by displacement of [125I]-Bolton-Hunter labeled eledoisin radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI