Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

LigandPNGBDBM50227987((6S,7S)-6-[4-(3,5-dimethyl-phenyl)-3,6-dihydro-2H-...)
Affinity DataIC50:  85nMAssay Description:Binding affinity to ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50227987((6S,7S)-6-[4-(3,5-dimethyl-phenyl)-3,6-dihydro-2H-...)
Affinity DataIC50:  86nMAssay Description:Inhibition of HER2 sheddase in BT474 cells by extracellular domain shedding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50227987((6S,7S)-6-[4-(3,5-dimethyl-phenyl)-3,6-dihydro-2H-...)
Affinity DataIC50:  433nMAssay Description:Binding affinity to MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50227987((6S,7S)-6-[4-(3,5-dimethyl-phenyl)-3,6-dihydro-2H-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Binding affinity to MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50227987((6S,7S)-6-[4-(3,5-dimethyl-phenyl)-3,6-dihydro-2H-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Binding affinity to MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50227987((6S,7S)-6-[4-(3,5-dimethyl-phenyl)-3,6-dihydro-2H-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Binding affinity to MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed