Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetApoptosis regulator Bcl-2/Glutathione S-transferase P(Homo sapiens (Human))
Abbvie

US Patent

LigandBDBM185627(US9156856, 40 | US9493431, 40)Copy SMILESCopy InChI

Affinity DataKi:  0.407nM ΔG°:  -53.6kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
DrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

US Patent

LigandBDBM185627(US9156856, 40 | US9493431, 40)Copy SMILESCopy InChI

Affinity DataKi:  0.407nM ΔG°:  -53.6kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI