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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex14 | US9115102, Ex24)
Affinity DataIC50:  35nMpH: 7.4Assay Description:The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel, 2006, 19, 155-161) and is added so as to hav...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex14 | US9115102, Ex24)
Affinity DataIC50:  35nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex14 | US9115102, Ex24)
Affinity DataIC50:  88nMpH: 7.4Assay Description:The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel, 2006, 19, 155-161) and is added so as to hav...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterstitial collagenase(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex14 | US9115102, Ex24)
Affinity DataIC50:  2.61E+3nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex14 | US9115102, Ex24)
Affinity DataIC50:  5.80E+3nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetStromelysin-1(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex14 | US9115102, Ex24)
Affinity DataIC50:  6.83E+3nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex14 | US9115102, Ex24)
Affinity DataIC50: >1.00E+4nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDisintegrin and metalloproteinase domain-containing protein 9(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex14 | US9115102, Ex24)
Affinity DataIC50: >1.00E+4nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In DepthDetails US Patent