Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

LigandBDBM50183718(CHEMBL208038 | tert-butyl 4-(hydroxycarbamoyl)-4-(...)Copy SMILESCopy InChI

Affinity DataIC50:  2.40nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL

LigandBDBM50183718(CHEMBL208038 | tert-butyl 4-(hydroxycarbamoyl)-4-(...)Copy SMILESCopy InChI

Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of LPS-stimulated TNFalpha production in human whole bloodMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI