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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50167494(5-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-5-(4-...)
Affinity DataKi:  83nMAssay Description:In vitro binding affinity against matrix metalloprotease 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50167494(5-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-5-(4-...)
Affinity DataKi:  85nMAssay Description:In vitro binding affinity against matrix metalloprotease 9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50167494(5-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-5-(4-...)
Affinity DataKi:  95nMAssay Description:In vitro binding affinity against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50167494(5-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-5-(4-...)
Affinity DataKi: >4.95E+3nMAssay Description:In vitro binding affinity against matrix metalloprotease 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50167494(5-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-5-(4-...)
Affinity DataIC50:  84nMAssay Description:In vitro inhibitory concentration against human tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed