Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAromatase(Homo sapiens (Human))
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50442323(CHEMBL2442759)
Affinity DataIC50:  6nMAssay Description:Inhibition of aromatase (unknown origin) using 7-methoxy-4-trifluoromethylcoumarin as substrate after 30 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50442323(CHEMBL2442759)
Affinity DataIC50:  75nMAssay Description:Inhibition of human CYP11B1 using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Padova

Curated by ChEMBL
LigandPNGBDBM50442323(CHEMBL2442759)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli using progesterone as substrate NADPH as cofactorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed