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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Neutrophil cytosol factor 1
(Homo sapiens)
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM10443
(2-methylquinolin-4-amine | 4-Aminoquinaldine 4)
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Affinity Data
Ki: 1.07E+6nM
Assay Description:
Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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MMDB
PC cid
PC sid
PDB
Patents
In Depth
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Article
PubMed
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Target
Acetylcholinesterase
(Rattus norvegicus (rat))
Hong Kong University Of Science And Technology
Ligand
BDBM10443
(2-methylquinolin-4-amine | 4-Aminoquinaldine 4)
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Affinity Data
IC50: 1.57E+4nM
pH: 7.4 T: 2°C
Assay Description:
The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
MMDB
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
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Target
Carboxylic ester hydrolase
(Rattus norvegicus (rat))
Hong Kong University Of Science And Technology
Ligand
BDBM10443
(2-methylquinolin-4-amine | 4-Aminoquinaldine 4)
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Affinity Data
IC50: 1.05E+5nM
Assay Description:
The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
MMDB
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
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Target
Pteridine reductase 1
(Leishmania major)
Rutgers University
Curated by
ChEMBL
Ligand
BDBM10443
(2-methylquinolin-4-amine | 4-Aminoquinaldine 4)
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Affinity Data
IC50: 3.90E+5nM
Assay Description:
Inhibition of Leishmania major PTR1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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MMDB
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neutrophil cytosol factor 1
(Homo sapiens)
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM10443
(2-methylquinolin-4-amine | 4-Aminoquinaldine 4)
Copy SMILES
Copy InChI
Affinity Data
Kd: 5.21E+5nM
Assay Description:
Binding affinity to immobilized recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cel...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
MMDB
PC cid
PC sid
PDB
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI