Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155571(US10092556, Example 17 | US9012475, 17 | US9346787...)
Affinity DataIC50:  0.900nMpH: 7.4 T: 2°CAssay Description:An inhibitory activity of the above compound in-vitro against Aurora A kinase activity was measured with reference to a method described in JP-A-2008...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155571(US10092556, Example 17 | US9012475, 17 | US9346787...)
Affinity DataIC50:  0.900nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155571(US10092556, Example 17 | US9012475, 17 | US9346787...)
Affinity DataIC50:  0.900nMpH: 7.4 T: 2°CAssay Description:For in vitro method for measuring the inhibitory activity of the aforementioned compounds on the aurora A kinase activity was carried out referring t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155571(US10092556, Example 17 | US9012475, 17 | US9346787...)
Affinity DataIC50:  900nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155571(US10092556, Example 17 | US9012475, 17 | US9346787...)
Affinity DataIC50:  900nMpH: 7.4Assay Description:The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM155571(US10092556, Example 17 | US9012475, 17 | US9346787...)
Affinity DataIC50:  900nMpH: 7.4Assay Description:The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca...More data for this Ligand-Target Pair
In DepthDetails US Patent