Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard University

Curated by ChEMBL
LigandPNGBDBM50123754((E)-(1S,2S,6S,7R)-2,6-Dihydroxy-1-(4-hydroxy-2,6-d...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]DAMGO from human Opioid receptor mu 1 expressing CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard University

Curated by ChEMBL
LigandPNGBDBM50123754((E)-(1S,2S,6S,7R)-2,6-Dihydroxy-1-(4-hydroxy-2,6-d...)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]diprenorphine from human Opioid receptor delta 1 epressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Harvard University

Curated by ChEMBL
LigandPNGBDBM50123754((E)-(1S,2S,6S,7R)-2,6-Dihydroxy-1-(4-hydroxy-2,6-d...)
Affinity DataKi:  260nMAssay Description:Displacement of 3H-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellum preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard University

Curated by ChEMBL
LigandPNGBDBM50123754((E)-(1S,2S,6S,7R)-2,6-Dihydroxy-1-(4-hydroxy-2,6-d...)
Affinity DataEC50:  4.20nMAssay Description:Compound tested at 10 uM for the ability to induce Opioid receptor mu 1-mediated binding of [35S]GTP-gamma-S to G proteins in CHO membrane preparatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed