Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Korea University Of Science And Technology

Curated by ChEMBL

LigandBDBM50062365(CHEMBL3397290)Copy SMILESCopy InChI

Affinity DataIC50:  108nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Korea University Of Science And Technology

Curated by ChEMBL

LigandBDBM50062365(CHEMBL3397290)Copy SMILESCopy InChI

Affinity DataIC50:  9.72E+3nMAssay Description:Inhibition of ALK (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Korea University Of Science And Technology

Curated by ChEMBL

LigandBDBM50062365(CHEMBL3397290)Copy SMILESCopy InChI

Affinity DataIC50:  7.34E+4nMAssay Description:Inhibition of ROS1 in human HCC78 cells after 48 hrs by CellTitre-Glo assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI