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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Integrin alpha-V/beta-3
(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50083789
(2-(3,5-Dimethyl-biphenyl-4-sulfonylamino)-3-({5-[4...)
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Affinity Data
IC50: 8.80nM
Assay Description:
Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Integrin alpha-IIb/beta-3
(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50083789
(2-(3,5-Dimethyl-biphenyl-4-sulfonylamino)-3-({5-[4...)
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Affinity Data
IC50: 690nM
Assay Description:
Inhibition of platelet aggregation in human gel-purified platelets containing fibrinogen (GPP+Fg).
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-IIb/beta-3
(Homo sapiens (Human))
Dupont Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50083789
(2-(3,5-Dimethyl-biphenyl-4-sulfonylamino)-3-({5-[4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.10E+3nM
Assay Description:
Inhibition of platelet aggregation in human platelet rich plasma (PRP)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI