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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S]
(Homo sapiens (Human))
H. Lundbeck
US Patent
Ligand
BDBM254924
(US9499542, 7 | US9675594, 7)
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Affinity Data
IC50: 78nM
pH: 8.5 T: 2°C
Assay Description:
LRRK2 kinase activity is measured using a LanthaScreen kinase activity assay available from Invitrogen (Life Technologies Corporation). The assay is ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Leucine-rich repeat serine/threonine-protein kinase 2
(Homo sapiens (Human))
H. Lundbeck
US Patent
Ligand
BDBM254924
(US9499542, 7 | US9675594, 7)
Copy SMILES
Copy InChI
Affinity Data
IC50: 620nM
pH: 8.5 T: 2°C
Assay Description:
LRRK2 kinase activity is measured using a LanthaScreen kinase activity assay available from Invitrogen (Life Technologies Corporation). The assay is ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Leucine-rich repeat serine/threonine-protein kinase 2 [970-2527,G2019S]
(Homo sapiens (Human))
H. Lundbeck
US Patent
Ligand
BDBM254924
(US9499542, 7 | US9675594, 7)
Copy SMILES
Copy InChI
Affinity Data
EC50: 78nM
Assay Description:
In the assay, 1 nM LRRK2 WT or 250 pM LRRK2 G2019S kinase is incubated with the test compound (typically at 0 to 30 μM) for 30 minutes before th...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Leucine-rich repeat serine/threonine-protein kinase 2 [970-2527]
(Homo sapiens (Human))
H. Lundbeck
US Patent
Ligand
BDBM254924
(US9499542, 7 | US9675594, 7)
Copy SMILES
Copy InChI
Affinity Data
EC50: 620nM
Assay Description:
In the assay, 1 nM LRRK2 WT or 250 pM LRRK2 G2019S kinase is incubated with the test compound (typically at 0 to 30 μM) for 30 minutes before th...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI