Home
About
Info
Download
WebServices
Contact
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat))
Bristol-Myers Squibb
US Patent
Ligand
BDBM198694
(US9221796, 23b)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.40nM ΔG°: -54.8kJ/mole
T: 2°C
Assay Description:
To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Glutamate receptor ionotropic, NMDA 2B
(Rattus norvegicus (Rat))
Bristol-Myers Squibb
US Patent
Ligand
BDBM198694
(US9221796, 23b)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.40nM
Assay Description:
Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development
Curated by
ChEMBL
Ligand
BDBM198694
(US9221796, 23b)
Copy SMILES
Copy InChI
Affinity Data
IC50: 400nM
Assay Description:
Inhibition of human ERG expressed in HEK293 cells assessed as reduction in peak tail current after 2 to 5 mins by patch clamp based electrophysiology...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI