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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Lysine-specific histone demethylase 1A [151-852]
(Homo sapiens (Human))
Incyte
US Patent
Ligand
BDBM103889
(US10047086, 3 | US10640503, Example 3 | US9695168,...)
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Affinity Data
IC50: <50nM
pH: 7.5 T: 2°C
Assay Description:
LANCE LSD1/KDM1A demethylase assay¿10 uL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 mM Na...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
Incyte
US Patent
Ligand
BDBM103889
(US10047086, 3 | US10640503, Example 3 | US9695168,...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <50nM
Assay Description:
LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
Incyte
US Patent
Ligand
BDBM103889
(US10047086, 3 | US10640503, Example 3 | US9695168,...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <50nM
pH: 7.5
Assay Description:
LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI