Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Vernalis (R&D)

LigandBDBM35795(pyrimidine-4-carboxamide, 71)Copy SMILESCopy InChI

Affinity DataKi:  36nMAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAdenosine receptor A1(Homo sapiens (Human))
Vernalis (R&D)

LigandBDBM35795(pyrimidine-4-carboxamide, 71)Copy SMILESCopy InChI

Affinity DataKi:  118nM ΔG°:  -39.0kJ/molepH: 7.5 T: 2°CAssay Description:Binding assays were performed in a total volume of 250 uL, containing radioligand, membranes and test compounds. Following 60 (A2B, A3) or 90 (A1, A2...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI