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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50158880
(CHEMBL3785783 | US10131664, Example 16 | US1054319...)
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Affinity Data
IC50: <10nM
Assay Description:
Inhibition of full length human KDM1A expressed in Escherichia coli using biotin-H3K4me1 as substrate incubated for 1 hr by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50158880
(CHEMBL3785783 | US10131664, Example 16 | US1054319...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <10nM
Assay Description:
Inhibition of KDM1A in human THP1 cells assessed as inhibition of CD11b expressing cells incubated for 4 days by DAPI staining based flow cytometry
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50158880
(CHEMBL3785783 | US10131664, Example 16 | US1054319...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <10nM
Assay Description:
The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50158880
(CHEMBL3785783 | US10131664, Example 16 | US1054319...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <100nM
Assay Description:
This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Lysine-specific histone demethylase 1A
(Homo sapiens (Human))
University Of Oxford
Curated by
ChEMBL
Ligand
BDBM50158880
(CHEMBL3785783 | US10131664, Example 16 | US1054319...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <100nM
Assay Description:
The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI