Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetKelch-like ECH-associated protein 1 [321-609](Homo sapiens (Human))
Glaxosmithkline

US Patent

LigandBDBM304723(3-(1,4-dimethyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-...)Copy SMILESCopy InChI

Affinity DataIC50:  55nMAssay Description:100 nL of 100× compound dose response curves (serial 3-fold dilutions) in DMSO are stamped using an Echo liquid handling system (Labcyte) into 384-we...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
Glaxosmithkline

US Patent

LigandBDBM304723(3-(1,4-dimethyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-...)Copy SMILESCopy InChI

Affinity DataEC50:  5.50E+3nMAssay Description:NAD(P)H:quinone oxidoreductase 1 (NQO1), also called DT diaphorase, is a homodimeric FAD-containing enzyme that catalyzes obligatory NAD(P)H-dependen...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI