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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50260942
(3-(2-aminoquinazolin-6-yl)-1-(3-fluoro-4-methylphe...)
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Affinity Data
IC50: 12nM
Assay Description:
Inhibition of SCF-induced phosphorylation of c-Kit (unknown origin) in MO7e cells by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50260942
(3-(2-aminoquinazolin-6-yl)-1-(3-fluoro-4-methylphe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
Inhibition of c-Kit (unknown origin) by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50260942
(3-(2-aminoquinazolin-6-yl)-1-(3-fluoro-4-methylphe...)
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Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of KDR (unknown origin) by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50260942
(3-(2-aminoquinazolin-6-yl)-1-(3-fluoro-4-methylphe...)
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Affinity Data
IC50: 2.50E+4nM
Assay Description:
Inhibition of Src (unknown origin) by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50260942
(3-(2-aminoquinazolin-6-yl)-1-(3-fluoro-4-methylphe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.50E+4nM
Assay Description:
Inhibition of Lck (unknown origin) by TR-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI