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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343083(CHEMBL1771218 | N-hydroxy-4-(4-(3-(5-(5-methylpyri...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343083(CHEMBL1771218 | N-hydroxy-4-(4-(3-(5-(5-methylpyri...)
Affinity DataKi:  3nMAssay Description:Inhibition of human MMP-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343083(CHEMBL1771218 | N-hydroxy-4-(4-(3-(5-(5-methylpyri...)
Affinity DataKi:  250nMAssay Description:Inhibition of human MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343083(CHEMBL1771218 | N-hydroxy-4-(4-(3-(5-(5-methylpyri...)
Affinity DataKi:  400nMAssay Description:Inhibition of human MMP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343083(CHEMBL1771218 | N-hydroxy-4-(4-(3-(5-(5-methylpyri...)
Affinity DataKi:  430nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343083(CHEMBL1771218 | N-hydroxy-4-(4-(3-(5-(5-methylpyri...)
Affinity DataKi:  970nMAssay Description:Inhibition of human MMP-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343083(CHEMBL1771218 | N-hydroxy-4-(4-(3-(5-(5-methylpyri...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343083(CHEMBL1771218 | N-hydroxy-4-(4-(3-(5-(5-methylpyri...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed