Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetMu-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105066(1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperi...)
Affinity DataIC50:  2.40nMAssay Description:Binding affinity against mu-opiate receptor (human) using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105066(1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperi...)
Affinity DataIC50:  2.40nMAssay Description:Binding affinity against mu opiate receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105066(1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperi...)
Affinity DataIC50:  2.90nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]- U-69,593 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105066(1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperi...)
Affinity DataIC50:  2.90nMAssay Description:Binding affinity against opioid receptor kappa 1 by using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105066(1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperi...)
Affinity DataIC50:  117nMAssay Description:Binding affinity against delta-opiate receptor (human) using [3H]-DPDPE radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105066(1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperi...)
Affinity DataIC50:  117nMAssay Description:Inhibition of ligand binding to human delta opioid receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105066(1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperi...)
Affinity DataIC50:  283nMAssay Description:Inhibition of human ORL1 orphanin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105066(1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperi...)
Affinity DataIC50:  556nMAssay Description:Binding affinity against M1 muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105066(1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperi...)
Affinity DataIC50:  663nMAssay Description:Inhibition of human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105066(1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperi...)
Affinity DataIC50:  1.71E+3nMAssay Description:Binding affinity against L-type calcium channel verapamil siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105066(1-[1-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-piperi...)
Affinity DataIC50:  4.92E+3nMAssay Description:Inhibition of alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed