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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
30
hits in this display
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
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Affinity Data
Ki: 0.316nM
Assay Description:
Mean negative logarithim of binding affinity was measured for the human 5-hydroxytryptamine 1A receptor; n>/=3
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.316nM
Assay Description:
Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.320nM
Assay Description:
Negative logarithm causing 50% receptor occupancy against 5-hydroxytryptamine 1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
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GoogleScholar
Ligand Info
CHEMBL
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Article
PubMed
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Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
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Affinity Data
Ki: 1.58nM
Assay Description:
Displacement of [3H]5HT from human cloned 5HT1D receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
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KEGG
UniProtKB/SwissProt
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Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.60nM
Assay Description:
Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.60nM
Assay Description:
Displacement of [3H]5-HT from human cloned 5HT1D receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.60nM
Assay Description:
Displacement of [3H]5HT from human recombinant 5HT1D receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.5nM
Assay Description:
Displacement of [3H]WAY100635 from human recombinant 5HT1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
antibodypedia
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Ligand Info
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.5nM
Assay Description:
Displacement of [3H]WAY-100635 from human cloned 5HT1A receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.5nM
Assay Description:
Displacement of [3H]WAY-100635 from human 5-hydroxytryptamine 1A receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.51nM
Assay Description:
Displacement of [3H]5HT from human cloned 5HT1A receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
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Affinity Data
Ki: 4nM
Assay Description:
Inhibition of [3H]5-HT binding to serotonin transporter in rat cortical synaptosomes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.30nM
Assay Description:
Mean negative logarithim of binding affinity was measured for the rat serotonin transporter; n>/=3
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Organon Laboratories
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.30nM
Assay Description:
Negative logarithm causing 50% receptor occupancy against serotonin transporter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7.90nM
Assay Description:
Inhibition of [3H]5-HT uptake at SERT in rat cortical synaptosomes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7.94nM
Assay Description:
Inhibition of [3H]5HT reuptake at SERT in rat cortical synaptosomes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 10nM
Assay Description:
Displacement of [3H]5-HT from human 5-hydroxytryptamine 1B receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 10nM
Assay Description:
Displacement of [3H]5HT from human cloned 5HT1B receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 10nM
Assay Description:
Inhibition of [3H]5HT uptake at SERT in rat cortical synaptosomes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 10nM
Assay Description:
Displacement of [3H]5HT from human recombinant 5HT1B receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: 10nM
Assay Description:
Displacement of [3H]5-HT from human cloned 5HT1B receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 7
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
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Affinity Data
Ki: 200nM
Assay Description:
Displacement of [3H]5CT from human cloned 5HT7a receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
Ligand Info
CHEMBL
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Organon Laboratories
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
Copy InChI
Affinity Data
Ki: <501nM
Assay Description:
Negative logarithm causing 50% receptor occupancy against beta-2 adrenergic receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
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Affinity Data
Ki: 631nM
Assay Description:
Displacement of [125I]iodosulpiride from human cloned D3 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
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Affinity Data
Ki: 1.26E+3nM
Assay Description:
Displacement of [125I]iodosulpiride from human cloned D2 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
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Affinity Data
Ki: 1.59E+3nM
Assay Description:
Displacement of [3H]5-HT from human cloned 5HT2B receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
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Affinity Data
Ki: 2.51E+3nM
Assay Description:
Binding affinity at adrenergic beta 1 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
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Affinity Data
Ki: 3.16E+3nM
Assay Description:
Displacement of [3H]ketanserin from human cloned 5HT2A receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
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Affinity Data
Ki: <7.94E+3nM
Assay Description:
Displacement of [3H]mesulergine from human cloned 5HT2C receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
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CHEMBL
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Article
PubMed
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Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50412114
(CHEMBL183460 | SB-649915)
Copy SMILES
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Affinity Data
Ki: <1.00E+4nM
Assay Description:
Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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antibodypedia
GoogleScholar
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