Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandPNGBDBM161468(US9108978, 6.09)
Affinity DataKi:  90nM ΔG°:  -41.8kJ/mole IC50:  530nMpH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
Monash University

US Patent
LigandPNGBDBM92383(Biotin triazole, 14)
Affinity DataKi:  90nMAssay Description:In vitro enzyme inhibition using biotin protein ligase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional ligase/repressor BirA(Escherichia coli)
Monash University

US Patent
LigandPNGBDBM161468(US9108978, 6.09)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional ligase/repressor BirA(Escherichia coli)
Monash University

US Patent
LigandPNGBDBM161468(US9108978, 6.09)
Affinity DataKi: >3.00E+4nM ΔG°: >-26.9kJ/molepH: 8.0 T: 2°CAssay Description:Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol...More data for this Ligand-Target Pair
In DepthDetails US Patent