Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAdenosine receptor A1(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL

LigandBDBM50262322(2-Amino-4-(3-methyl-phenyl)-6-furan-2-yl-nicotinon...)Copy SMILESCopy InChI

Affinity DataKi:  64nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetAdenosine receptor A2a(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL

LigandBDBM50262322(2-Amino-4-(3-methyl-phenyl)-6-furan-2-yl-nicotinon...)Copy SMILESCopy InChI

Affinity DataKi:  140nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAdenosine receptor A2b(Homo sapiens (Human))
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL

LigandBDBM50262322(2-Amino-4-(3-methyl-phenyl)-6-furan-2-yl-nicotinon...)Copy SMILESCopy InChI

Affinity DataKi:  620nMAssay Description:Displacement of [3H]MRS1754 from human adenosine A2B receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI